Pleuromutilin derivatives having antibacterial activity

Details Pleuromutilin derivatives having antibacterial activity Pleuromutilin derivatives having antibacterial activity

C - Chemistry, Metallurgy

07

C

C07C 323/61 (2006.01) A61K 31/215 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2412932

A compound selected from 14-O-[(cycloalkylsulfanyl)acetyl]mutilins; 14-O-[(cycloalkyl-alkylsulfanyl)acetyl] mutilins; 14-O-[(cycloalkoxy)acetyl] mutilins; and 14-O-[(cycloalkyl-alkoxy)acetyl] mutilins and its use for treating a microbial disease. The compound may have the following formula: (see above formula).

L'invention concerne un composé choisi parmi 14-O-[(cycloalkyle-sulfanyle)acétyle]mutilines; 14-O-[(cycloalkyle-alkyle-sulfanyle)acétyle]mutilines; 14-O-[(cycloalcoxy)acétyle]mutilines; ou 14-O-[(cycloalkyle-alcoxy)acétyle]mutilines, ainsi que son utilisation comme produit pharmaceutique.

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