Pleuromutilin derivatives process for their preparation and...

C - Chemistry – Metallurgy – 07 – D

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167/233, 167/252

C07D 277/06 (2006.01) C07D 207/16 (2006.01) C07C 149/26 (1985.01)

Patent

CA 1249281

PLEUROMUTILIN DERIVATIVES PROCESS FOR THEIR PREPARATION AND THEIR USE Abstract of the Disclosure A compound of formula I Image I wherein R1 represents ethyl or vinyl and and R2 represents a five membered saturated heterocycle or amino- alkyl unsubstituted or substituted in its alkyl moiety by hydroxy, in free form or in the form of an acid addition or quaternary salt, which compounds are indicated for use as chemotherapeutic agents e.g. as anti-bacterially active antibiotics and as veterinary agents e.g. in combatting microorganism infections and promoting growth in domestic animals.

474419

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