C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 5/22 (2006.01)
Patent
CA 2599784
The present invention provides a genetically modified cell comprising a polynucleotide sequence integrated into the ENVY locus from chromosome 12. The ENVY locus advantageously provides a conduit for the ubiquitous or cell type specific expression of heterologous genes in human stem cells.
La présente invention concerne une cellule modifiée génétiquement qui comprend une séquence de polynucléotides intégrée dans le locus ENVY du chromosome 12. Le locus ENVY procure de façon avantageuse un conduit pour l~expression ubiquitaire ou spécifique d~un type cellulaire de gènes hétérologues dans des cellules souches humaines.
Costa Magdaline
Dottori Mirella
Elefanty Andrew
Pera Martin
Stanley Edouard
Australian Stem Cell Centre Limited
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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