Pluripotent stem cell differentiation by using human feeder...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/0735 (2010.01) C12N 5/071 (2010.01) A61K 35/12 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2694956

The present invention relates to the field of pluripotent stem cell differentiation. The present invention provides methods for the differentiation of pluripotent stem cells on a human feeder cell layer. In particular, the present invention provides an improved method for the differentiation of pluripotent stem cells into pancreatic endocrine cells using a human feeder cell layer.

L'invention concerne le domaine de la différenciation des cellules souches pluripotentes. La présente invention concerne également des méthodes de différenciation des cellules souches pluripotentes sur une couche de cellules d'alimentation humaines. La présente invention concerne, en particulier, une méthode améliorée de différenciation des cellules souches pluripotentes dans des cellules endocrines pancréatiques à l'aide d'une couche de cellules d'alimentation humaine.

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