Plus end-directed microtubule motor required for chromosome...

Details Plus end-directed microtubule motor required for chromosome... Plus end-directed microtubule motor required for chromosome...

C - Chemistry, Metallurgy

12

N

C12N 9/16 (2006.01) C07K 14/46 (2006.01) C07K 16/18 (2006.01) C07K 16/40 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/55 (2006.01) C12Q 1/44 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2303484

The invention provides isolated nucleic acid and amino acid sequences of Xenopus CENP-E (XCENP-E), antibodies to XCENP-E, methods of screening for CENP- E modulators using biologically active CENP-E, and kits for screening for CENP- E modulators.

L'invention a trait à des séquences d'acides nucléiques et d'acides aminés isolés de CENP-E (protéine E associée au centromère) de Xenopus (XCENP-E), à des anticorps anti-XCENP-E, à des procédés de criblage de modulateurs de CENP-E au moyen de CENP-E biologiquement active, et à des trousses utiles pour le criblage de modulateurs de CENP-E.

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