Pm-2 antibodies and methods for treating metastasis

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61P 35/04 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2710347

The invention provides PM-2 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a PM-2 antibody or functional fragment thereof effective to treat metastasis of the neoplasia, tumor or cancer in the subject.

L'invention porte sur des anticorps PM-2, des fragments fonctionnels, des formes modifiées et variantes, un acide nucléique et autres compositions. Des anticorps, fragments fonctionnels, formes modifiées et variantes, un acide nucléique et autres compositions sont utiles dans des procédés de traitement et de diagnostic. Un procédé comprend le traitement de la métastase d'une néoplasie, d'une tumeur ou d'un cancer chez un sujet ayant besoin d'un traitement par l'administration au sujet d'une quantité d'un anticorps PM-2 ou d'un fragment fonctionnel de celui-ci efficace pour traiter une métastase de la néoplasie, de la tumeur ou du cancer chez le sujet.

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