Pna and dna conjugates and methods for preparation thereof

Details Pna and dna conjugates and methods for preparation thereof Pna and dna conjugates and methods for preparation thereof

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 47/48 (2006.01) C07F 9/24 (2006.01) C07H 21/00 (2006.01) C07K 1/107 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2320390

Disclosed herein are methods for linking a protein or other biomolecule containing a carboxylic acid moiety to a PNA or DNA probe molecule. The methods disclosed herein involve activating the carboxylic acid moiety with an activating agent and reacting the activated carboxylic acid moiety with a PNA or DNA probe having an arylamine or aminooxyacetyl moiety. Conjugates produced by these methods are also disclosed.

On décrit des procédés de liaison d'une protéine ou autre biomolécule contenant une fraction d'acide carboxylique à une molécule sonde d'ANP ou d'ADN. Les procédés de l'invention consistent à activer la fraction d'acide carboxylique au moyen d'un activateur, et à faire réagir ladite fraction d'acide carboxylique activée avec une sonde d'ANP ou d'ADN comprenant une fraction arylamine ou amino-oxyacétyle. On décrit en outre des conjugués produits au moyen desdits procédés.

Affiliated with

Also associated with

Rating

Pna and dna conjugates and methods for preparation thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pna and dna conjugates and methods for preparation thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pna and dna conjugates and methods for preparation thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1423912