Pna combinatorial libraries and improved methods of synthesis

Details Pna combinatorial libraries and improved methods of synthesis Pna combinatorial libraries and improved methods of synthesis

C - Chemistry, Metallurgy

07

K

C07K 2/00 (2006.01) C07K 1/04 (2006.01) C07K 1/06 (2006.01) C07K 1/10 (2006.01) C07K 7/02 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2183371

New sub-monomer synthetic methods for the preparation of peptide nucleic acid oligomeric structures are disclosed that provide for the synthesis of both predefined sequence peptide nucleic acid oligomers as well as random sequence peptide nucleic acid oligomers. Further these methods also provide for the incorporation of peptide nucleic acid units or strings of such units with amino acids or strings of amino acids in chimeric peptide nucleic acid-amino acid compounds. Further disclosed are methods of making random libraries of peptide nucleic acids using the fully preformed monomers.

L'invention concerne de nouveaux procédés de synthèse de sous-monomères destinés à la préparation de structures oligomères d'acides nucléiques peptidiques, assurant la synthèse à la fois d'oligomères d'acides nucléiques peptidiques à sequences prédéfinies et d'oligomères d'acides nucléiques peptidiques à séquences aléatoires. Ces procédés comprennent également l'incorporation d'unités d'acides nucléiques peptiques ou de chaînes de ces unités et à des acides aminés ou des chaînes d'acides aminés dans des composés chimères d'acides nucléiques peptidiques et d'acides aminés. L'invention concerne en outre un procédé de production de banques aléatoires d'acides nucléiques peptidiques utilisant les monomères entièrement préformés.

Affiliated with

Also associated with

Rating

Pna combinatorial libraries and improved methods of synthesis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pna combinatorial libraries and improved methods of synthesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pna combinatorial libraries and improved methods of synthesis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1717040