A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/09 (2006.01)
Patent
CA 2633772
The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multi-valent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.
La présente invention concerne des vaccins pneumococciques à base de conjugués de saccharides capsulaires. Plus particulièrement, elle concerne une composition immunogène de Streptococcus pneumoniae comprenant plusieurs saccharides capsulaires conjugués issus de différents sérotypes de S. pneumoniae conjugués à au moins 2 protéines-supports différentes, la composition comprenant un saccharide capsulaire de sérotype 19F conjugué à une anatoxine diphtérique (DT) ou CRM197, 19F étant éventuellement le seul saccharide dans la composition conjugué à une anatoxine diphtérique (DT) ou CRM197.
Biemans Ralph Leon
Garcon Nathalie Marie-Josephe
Hermand Philippe Vincent
Poolman Jan
Van Mechelen Marcelle Paulette
Glaxosmithkline Biologicals S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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