Pneumocystis carinii dihydrofolate reductase gene and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/53 (2006.01) C12N 1/21 (2006.01) C12N 9/02 (2006.01) C12N 9/06 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2045184

2045184 9107419 PCTABS00005 Genetic material encoding dihydrofolate reductase (DHFR) of Pneumocystis carinii has been isolated and characterized. This genetic material allows the production of peptides for use in the design of inhibitors specific for P. carinii DHFR (as opposed to DHFR in the host infected with P. carinii) or can itself be directly used in hybridization assays.

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