Polar dyes

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/80 (2006.01) C07H 21/00 (2006.01) C09K 11/06 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2599709

The present invention relates to novel polar fluorescent and quenchers dyes, and minor groove binder with enhanced polarity. The present invention further relates to methods of preparing oligonucleotide probes labeled with polar arsonate dyes under the condition of automated synthesis and method of using such probes.

La présente invention concerne des nouvelles teintures polaires fluorescentes et extinctrices polaires, et un agent de liaison au petit sillon de polarité accrue. Cette invention concerne également des méthodes d'obtention d'oligonucléotides marqués avec des teintures polaires d'arsonate en conditions de synthèse automatisée et une méthode d'utilisation de telles sondes.

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