Polar silanes for binding to substrates and use of the bound...

C - Chemistry – Metallurgy – 07 – F

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C07F 7/18 (2006.01) B01J 20/291 (2006.01)

Patent

CA 2544636

Polyfunctional silicon compounds having one of the following structures: wherein at least one of R1, R2 and R3 is a leaving group which, after leaving, permits the Si in one of said structures to form a Si-O-Si or Si-O-Zr bond, wherein L1, L2 and L3 comprise alkyl or substituted alkyl chains from 1 to 100 in length, wherein m = 1-100; wherein N - PG, N - PG1 and N - PG2 are nitrogen- containing polar groups; wherein each of E, E1, and E2 comprise alkyl, substituted alkyl, aryl, or substituted aryl groups, comprising 1-50 carbon atoms, and exclude functional groups selected from the group consisting of hydroxyl, carboxyl, amino, thio, halo and sulfonate moieties. Also, such compounds bound to substrates for use as chromatography.packing.

L'invention concerne des composés de silicium polyfonctionnels représentés par les structures suivantes (I) et (II), dans lesquelles : au moins un élément parmi R¿1?,¿ ?R¿2? et R¿3? est un groupe partant qui, après le départ, permet au Si dans une desdites structures de former une liaison Si-O-Si ou Si-O-Zr ; L¿1?, L¿2? et L¿3? comprennent des chaînes alkyle ou alkyle substitué de longueur comprise entre 1 et 100 ; m = 1-100 ; N - PG, N - PG¿1? et N - PG¿2? sont des groupes polaires contenant de l'azote ; chaque élément parmi E, E¿1?, et E¿2? comprend des groupes alkyle, alkyle substitué, aryle, ou aryle substitué, comportant entre 1 et 50 atomes de carbone, et est exempt de groupes fonctionnels sélectionnés dans le groupe comprenant fragments hydroxyle, carboxyle, amino, thio, halo et sulfonate. Lesdits composés de l'invention se lient à des substrats destinés à être utilisés en tant que garnissage d'une colonne chromatographique.

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