Polipeptide compounds for inhibiting angiogenesis and tumor...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/705 (2006.01) A61K 38/00 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2581423

In certain embodiments, this present invention provides polypeptide compositions,including compositions a modified polypeptide, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.

Dans certains modes de réalisation, la présente invention a trait à des compositions de polypeptides, comprenant des compositions contenant un polypeptide modifié, et à des procédés pour l'inhibition de l'activité d'Ephrine B2 ou d'EphB4. Dans d'autres modes de réalisation, la présente invention a trait à des compositions pour le traitement du cancer ou pour le traitement de maladies associées à l'angiogenèse.

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