Poloxamer foamable pharmaceutical compositions with active...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 8/04 (2006.01) A61K 8/90 (2006.01) A61K 9/12 (2006.01) A61K 31/196 (2006.01) A61K 31/60 (2006.01) A61K 47/10 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2712120

Pharmaceutical or cosmetic compositions and methods for their use are provided comprising water and a surfactant polymer system comprising a Poloxamer at a concentration of about 0.1 % to about 15% by weight; wherein when the Poloxamer is between about 0.1 % to about 5% Poloxamer. The composition can further comprise a supporting agent comprising a non-ionic surface active agent or a supporting agent comprising a non surfactant polymer or polysaccharide and an active agent, where the Poloxamer is capable of fixing the composition on delivery to a body surface. There are further provided therapeutic cell composi-tions and their uses.

L'invention porte sur des compositions pharmaceutiques ou cosmétiques et sur leurs procédés d'utilisation, ces compositions comportant de l'eau et un système polymère tensioactif qui comporte un poloxamère à une concentration d'environ 0,1 % à environ 15 % en poids, le poloxamère représentant entre environ 0,1 % à environ 5 %. La composition peut en outre comporter un agent de support qui comporte un agent de surface non ionique actif ou un agent de support qui comporte un polymère non tensioactif ou polysaccharide et un agent actif, le poloxamère étant capable de fixer la composition lors de l'administration à une surface du corps. L'invention porte en outre sur des compositions de cellules thérapeutiques et sur leurs utilisations.

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