A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61K 31/785 (2006.01) A61K 31/787 (2006.01) A61K 31/795 (2006.01) A61K 47/48 (2006.01) C08G 61/12 (2006.01)
Patent
CA 2276394
The present invention relates to a method for removing bile acids from a patient and certain polymers of use in the method. The method comprises the step of administering to the patient a therapeutically effective amount of a polymer composition which includes a poly(diallylamine) polymer which is substituted with hydrophobic groups. The hydrophobic groups can be a substituted or unsubstituted, straight chain or branched C3-C24-alkyl group, an aralkyl group or an aryl group.
La présente invention concerne un procédé permettant d'éliminer des acides biliaires d'un patient, ainsi que certains polymères destinés à être utilisés dans ce procédé. Ce procédé consiste à administrer au patient une dose thérapeutiquement efficace d'une composition polymère qui renferme un polymère de poly(diallylamine) substitué par des groupes hydrophobes. Ces groupes hydrophobes peuvent être un groupe alkyle en C¿3?-C¿24? à chaîne linéaire ou ramifiée, substitué ou non substitué, un groupe aralkyle ou un groupe aryle.
Dhal Pradeep K.
Holmes-Farley Stephen Randall
Petersen John S.
Geltex Pharmaceuticals Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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