Poly(ether-thioether), poly(ether-sulfoxide) and...

Details Poly(ether-thioether), poly(ether-sulfoxide) and... Poly(ether-thioether), poly(ether-sulfoxide) and...

C - Chemistry, Metallurgy

07

D

C07D 473/00 (2006.01) A01N 43/54 (2006.01) A01N 43/90 (2006.01) A61K 31/795 (2006.01) A61K 48/00 (2006.01) C07D 239/00 (2006.01) C07H 19/10 (2006.01) C07H 19/20 (2006.01) C07H 21/00 (2006.01) C08G 65/34 (2006.01) C08G 65/48 (2006.01) C12N 15/63 (2006.01) C12N 1/08 (2006.01)

Patent

CA 2382631

A compound comprising a poly(ether-thioether), poly(ether-sulfoxide) or poly(ether-sulfone) backbone bearing a plurality of ligands that are individually bound to chiral carbon atoms located within the backbone, at least one of the ligands includ-ing a moiety such as a naturally occurring nucleobase, a nucleobase binding group or a DNA interchelator; a process of synthesizing the compound, monomers to be used in this process and their synthesis process and processes for using the compound in biochem-istry and medicine.

L'invention concerne un composé comprenant un squelette de poly(éther-thioéther), de poly(éther-sulfoxyde) ou de poly(éther-sulfone) servant de support à une pluralité de ligands individuellement liés à des atomes de carbone chiraux se trouvant à l'intérieur dudit squelette, l'un de ces ligands au moins comprenant un groupe caractéristique, tel qu'une nucléobase naturelle, un groupe de liaison de nucléobases ou un interchélateur d'ADN. L'invention concerne également un procédé de synthèse de ce composé, des monomères intervenant dans ce procédé et leur procédé de synthèse, et des procédés d'utilisation de ce composé en biochimie et en médecine.

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