Poly-gamma-glutamate having ultra high molecular weight and...

C - Chemistry – Metallurgy – 08 – H

Patent

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C08H 1/00 (2006.01) A61K 47/42 (2006.01) C07K 14/32 (2006.01) C12P 21/02 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2490976

The present invention relates to a poly-gamma-glutamate (PGA) having an ultra- high molecular weight greater than 5,000 kDa. The ultra-high molecular weight PGA according to the present invention has a mean molecular weight greater than 13,000 kDa, and more than 95 % of its molecules have a molecular weight ranging from 3,000 to 15,000 kDa. Also, it can be produced by the culturing ofBacillus subtilis var. chungkookjang. The ultra-high molecular weight PGA according to the present invention shows very excellent moisture-absorbing, moisture-retaining, sustained release, mineral solubility, and water-absorbing properties, and thus, can be used as a new and high value-added material in various applications.

La présente invention concerne un poly-gamma-glutamate (PGA) possédant un poids moléculaire extrêmement élevé supérieur à 5 000 kDa. Selon ladite invention, ce poly-gamma-glutamate (PGA) à poids moléculaire extrêmement élevé a un poids moléculaire moyen supérieur à 13 000 kDa, et plus de 95 % de ses molécules ont un poids moléculaire compris entre 3 000 et 15 000 kDa. On peut le produire en cultivant Bacillus subtilis var. chungkookjang. Ledit poly-gamma-glutamate (PGA) présente d'excellentes propriétés d'absorption de l'humidité, de rétention de l'humidité, de libération soutenue, de solubilité minérale et d'absorption d'eau, et on peut l'utiliser comme une nouvelle matière à valeur ajoutée élevée dans diverses applications.

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