Poly-heteroaryl derivatives for the treatment of cancer

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/14 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/496 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2740558

The present invention relates to Penta- hexa-, hepta-, octa-, nona- and, deca- heteroaryl derivatives, comprising a combination of heterocycle 1(Het-1)a and/or heterocycie 2 (Het-2)b and/ or heterocycle 3(Het-3)c and/or heterocycle 4(Het-4)d of formulae I, II, III and IV respectively, the N-oxides, the pharmaceutically acceptable addition salts. The compounds claimed are suitable for the treatment of cancer.

La présente invention concerne des dérivés de penta- hexa-, hepta-, octa-, nona- et déca-hétéroaryle comprenant une combinaison d'hétérocycle 1 (Het-1)a et/ou d'hétérocycle 2 (Het-2)b et/ou dhétérocycle 3 (Het-3)c et/ou d'hétérocycle 4 (Het-4)d respectivement de formules I, II, III et IV, leurs N-oxydes, leurs sels d'addition pharmaceutiquement acceptables. Les composés de l'invention sont appropriés pour le traitement du cancer

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