Poly-pegylated protease inhibitors

Details Poly-pegylated protease inhibitors Poly-pegylated protease inhibitors

A - Human Necessities

61

K

A61K 38/00 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2536873

Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease; and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.

L'invention concerne des composés qui comprennent: (i) un polypeptide du domaine de Kunitz comprenant un domaine de Kunitz qui se lie à une protéase et qui l'inhibe; (ii) plusieurs fractions de polyéthylène glycol fixées au polypeptide du domaine de Kunitz. Chaque amine primaire accessible du polypeptide du domaine de Kunitz peut être fixée à l'une desdites fractions. L'invention concerne enfin des procédés associés.

Affiliated with

Also associated with

Rating

Poly-pegylated protease inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Poly-pegylated protease inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Poly-pegylated protease inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1415826