C - Chemistry – Metallurgy – 08 – G
Patent
C - Chemistry, Metallurgy
08
G
167/37, 402/524,
C08G 69/00 (2006.01) A61K 39/385 (2006.01) A61K 47/48 (2006.01) C07K 1/04 (2006.01) C07K 17/08 (2006.01) C08F 220/56 (2006.01) G01N 33/543 (2006.01) G01N 33/545 (2006.01)
Patent
CA 1339670
A polyamide resin for use in peptide protein-synthesis and a method of preparing and using same. The polyamide resin is prepared by cross-linking a dimethylacrylamide monomer by co-polymerization with a functional monomer in an aqueous solution, emulsifying the aqueous solution in an organic solvent and isolating the polyamide resin beads formed by adding an initiator and a promotor. The beads are used as a solid phase for peptide and protein synthesis according to methods known in the art. The conjugate of the polyamide resin and the synthesized peptide or protein is used directly for immunoassays or immunization without the need for separation of the peptide or protein from the resin and subsequent purification.
535982
Kanda Patrick
Kennedy Ronald C.
Sparrow James T.
Baylor College Of Medicine
Sim & Mcburney
Southwest Foundation For Biomedical Research
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