Polyamine derivatives as anti-cytomegaloviral agents

Details Polyamine derivatives as anti-cytomegaloviral agents Polyamine derivatives as anti-cytomegaloviral agents

A - Human Necessities

61

K

A61K 31/13 (2006.01) A61K 31/135 (2006.01) C07C 211/14 (2006.01) C07C 211/27 (2006.01)

Patent

CA 2146319

The present invention relates to treating CMV infections with polyamine compounds of formula (I) wherein Z is a saturat- ed or branched chain (C2-C6) alkylene moiety; m is 7 or 8; each R group independently is hydrogen, a C1-C6 saturated or unsaturated hydrocarbyl, or -(CH2)x-(Ar)-X wherein Ar is phenyl or napthyl, X is H, C1-C6 alkoxy, halogen C1-C4 alkyl, wherein x is an integer 0, 1, or 2; with the proviso that both R groups cannot be hydrogen; or said compounds of formula (I) can be a pharmaceutically acceptable acid addition salt thereof.

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