Polyamines and their use in therapy

Details Polyamines and their use in therapy Polyamines and their use in therapy

C - Chemistry, Metallurgy

07

D

C07D 487/22 (2006.01) A61K 31/13 (2006.01) A61K 31/155 (2006.01) A61K 31/40 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07C 45/46 (2006.01) C07C 67/343 (2006.01) C07C 211/18 (2006.01) C07C 211/22 (2006.01) C07C 211/23 (2006.01) C07C 211/36 (2006.01) C07C 215/14 (2006.01) C07C 257/18 (2006.01) C07D 207/34 (2006.01) C07D 219/10 (2006.01) C07D 235/18 (2006.01) C07D 295/185 (2006.01) C07D 307/79 (2006.01) C07D 307/92 (2006.01) C07D 311/92 (2006.01) C07D 317/70 (2006.01) C07D 493/04 (2006.01) C07K 5/103

Patent

CA 2371625

Novel conformationally restricted polyamine analogs are provided, as well as compositions comprising these novel polyamine analogs. Methods of using the novel polyamine analogs in treatment of diseases such as cancer are also provided. Also provided is a method of delivering these analogs specifically to tumor cells by covalently attaching polyamine analogs to porphyrin compounds, along with novel polyamine-porphyrin covalent conjugates.

L'invention concerne de nouveaux analogues de polyamine à conformation restreinte ainsi que des compositions renfermant ces nouveaux analogues de polyamine. Cette invention concerne également des méthodes d'utilisation de ces nouveaux analogues de polyamine pour traiter des maladies comme le cancer, et des méthodes permettant un apport spécifique de ces analogues à des cellules tumorales, par liaison covalente entre lesdits analogues de polyamine et des composés de porphyrine, avec de nouveaux conjugués de polyamine-porphyrine covalents.

Affiliated with

Also associated with

Rating

Polyamines and their use in therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polyamines and their use in therapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polyamines and their use in therapy will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1702914