Polycarbonate membranes and production thereof

Details Polycarbonate membranes and production thereof Polycarbonate membranes and production thereof

C - Chemistry, Metallurgy

08

J

18/24

C08J 9/28 (2006.01) A61M 1/14 (2006.01) B01D 39/16 (2006.01) B01D 67/00 (2006.01) B01D 71/06 (2006.01) C08G 65/00 (2006.01) C08J 5/18 (2006.01) C08J 5/22 (2006.01)

Patent

CA 1062413

POLYCARBONATE MEMBRANES AND PRODUCTION THEREOF ABSTRACT OF THE DISCLOSURE Polycarbonate membranes useful for hemodialysis are fabricated from polyether-polycarbonate block copolymers by a water gelation process. The process comprises casting on to a substrate surface a layer of a multicomponent casting solution comprising the copolymer dissolved in a water-miscible organic solvent together with a cosolvent which acts as a swelling agent for the copolymer, drying the layer to partially evaporate the solvents therefrom, immersing the partially dried layer in water to form a gelled membrane, and stripping the gelled membrane from the substrate surface. The membrane has improved strength and improved permeability to solutes in the "middle molecule" range while maintaining clinically acceptable ultrafiltration rates and clearance of low molecular weight solutes.

222510

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