Polycationic antimicrobial therapeutic

Details Polycationic antimicrobial therapeutic Polycationic antimicrobial therapeutic

A - Human Necessities

61

K

A61K 33/38 (2006.01) A61K 31/155 (2006.01)

Patent

CA 2565556

Methods of treatment for medical indications having a microbial etiology are provided using polybiguanides, particularly water insoluble and complexed with a water insoluble antimicrobial metal material. The compositions are contacted with mucosal or dermal tissue susceptible to infection or infected in an amount sufficient to inhibit proliferation and with a spaced-apart regimen due to the persistence of the composition.

L'invention concerne des méthodes de traitement pour des indications médicales d'étiologie microbienne faisant intervenir des polybiguanides, en particulier insolubles dans l'eau et formant un complexe avec un matériau métallique antimicrobien insoluble dans l'eau. Les compositions de l'invention sont mises en contact avec des tissus muqueux ou dermiques sensibles à une infection ou suffisamment infectés afin d'inhiber la prolifération et selon un régime espacé en raison de la persistance desdites compositions.

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