C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
195/1.12, 150/8.
C07H 21/00 (2006.01) C07H 1/06 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 1339446
Described herein is the use of polycationic solid supports in the purification of nucleic acids from solutions containing contaminants. The nucleic acids non-covalently bind to the support without signficant binding of contaminants permitting their separation from the contaminants. The bound nucleic acids can be recovered from the support. Also described is the use of the supports as a means to separate polynucleotides and hybrids thereof with a nucleotide probe from unhybridized probe. Assays for target nucleotide sequences are described which employ this separation procedure.
560293
Arnold Lyle J. Jr.
Nelson Norman C.
Reynolds Mark A.
Waldrop Alexander A. III
Arnold Lyle J. Jr.
Gen-Probe Inc.
Nelson Norman C.
Reynolds Mark A.
Smart & Biggar
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