(polycyclic-arylmethoxy)indoles as inhibitors of leukotriene...

Details (polycyclic-arylmethoxy)indoles as inhibitors of leukotriene... (polycyclic-arylmethoxy)indoles as inhibitors of leukotriene...

C - Chemistry, Metallurgy

07

D

C07D 209/18 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) C07D 209/22 (2006.01) C07D 401/02 (2006.01) C07D 403/02 (2006.01) C07D 405/02 (2006.01) C07D 409/02 (2006.01) C07D 413/02 (2006.01) C07D 417/02 (2006.01)

Patent

CA 2079083

F2 224/GL93 225/GL94 18571 TITLE OF THE INVENTION (POLYCYCLIC-ARYLMETHOXY)lNDOLES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS ABSTRACT OF THE DISCLOSURE Compounds having the formula I: Image I are inhibitore of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti- allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.

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