Polycyclic carbapenem compounds, their production and use

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/04 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) C07D 471/14 (2006.01) C07D 477/00 (2006.01) C07D 491/147 (2006.01) C07D 495/14 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2065079

A polycyclic carbapenem compound of the formula (Ia'), (Ib') or (Ic') Image [wherein COOR2 is a carboxy group which may be esterified; Ra' is -(CH2)m-Fa-(CH2)n-U2; J is O or S; Rb' is -(CH2)m-Kb -(CH2)n-Ub' ; J' is O, S or CH2; Rc' is - (CH2) m-Rc- (CH2)n-Uc' , -(CH2) m-Kd- (CH2) n-Ud or a pair of groups, one of which is a hydroxy group, with the other being a hydroxy group or an alkylsuifonylamino group, which may be substituted, in the position ortho to the first-mentioned hydroxy group] or a salt thereof are useful as an antibacterial agent.

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