C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/4196 (2006.01) A61P 19/00 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01) C07D 451/04 (2006.01) C07D 471/04 (2006.01) C07D 471/18 (2006.01) C07D 487/04 (2006.01) C07D 487/10 (2006.01) C07D 491/04 (2006.01) C07D 491/14 (2006.01) C07D 491/20 (2006.01) C07D 495/04 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2710234
Polycyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Ax1. Methods of using the compounds in treating diseases or conditions associated with Ax1 activity are also disclosed.
L'invention concerne des triazoles substitués par hétéroaryle polycyclique et des compositions pharmaceutiques contenant les composés comme étant utiles pour l'inhibition de l'activité de la protéine tyrosine kinase réceptrice de Axl. Des procédés d'utilisation des composés pour le traitement de maladies ou d'états associés à l'activité de Axl sont également décrits.
Ding Pingyu
Goff Dane
Heckrodt Thilo
Holland Sacha
Litvak Joane
Gowling Lafleur Henderson Llp
Rigel Pharmaceuticals Inc.
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