C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/502 (2006.01) A61K 31/5025 (2006.01) A61P 35/00 (2006.01) C07D 471/14 (2006.01)
Patent
CA 2730231
Polycyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are dis-closed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Ax1 activity are also disclosed.
La présente invention concerne des triazoles à substitution hétéroaryle polycycliques et des compositions pharmaceutiques renfermant les composés, étant utiles dans linhibition de lactivité du récepteur protéine tyrosine kinase Axl. Linvention a également pour objet des procédés dutilisation des composés dans le traitement de maladies ou daffections associées à lactivité Axl.
Heckrodt Thilo J.
Holland Sacha
Singh Rajinder
Gowling Lafleur Henderson Llp
Rigel Pharmaceuticals Inc.
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