Polycyclo heterocyclic derivatives as antiinflammatory agents

Details Polycyclo heterocyclic derivatives as antiinflammatory agents Polycyclo heterocyclic derivatives as antiinflammatory agents

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/38 (2006.01) A61K 31/517 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2360934

Disclosed are novel aromatic polycyclo heterocyclic compounds of formula (I) wherein A, B, C, G, Ar, L, Q and X are described herein. The compounds are useful in pharmaceutical compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes of making such compounds.

L'invention se rapporte à de nouveaux composés aromatiques polycyclo hétérocycliques représentés par la formule (I) dans laquelle A, B, C, G, Ar, L Q et X sont définis dans la description associée. Ces composés s'avèrent utiles dans des compositions pharmaceutiques destinées au traitement de maladies ou d'affections pathologiques associées à une inflammation telles que les maladies inflammatoires chroniques. L'invention se rapporte également à des procédés de fabrication de tels composés.

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