Polydiazeniumdiolated cyclic polyamines with polyphasic...

C - Chemistry – Metallurgy – 07 – D

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C07D 259/00 (2006.01) A61K 31/395 (2006.01) A61P 9/00 (2006.01) A61P 15/00 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01) C07D 255/00 (2006.01) C07D 255/02 (2006.01) C07D 257/02 (2006.01)

Patent

CA 2485167

The present invention provides compound of the Formula (I); in which at least two of R1, R2, R3, R4, R5, and R6 are N2O2M and related compounds, substrates, compositions, and methods of using such compounds and compositions to treat biological disorders in which a polyphasic release of nitric oxide would be beneficial.

L'invention porte sur des composés de formule (I) dans laquelle: au moins deux de R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, et R?6¿ sont N¿2?O¿2?M, ainsi que sur des composés, substrats, compositions, associés et sur les méthodes d'utilisation desdits composés et compositions pour le traitement de troubles biologiques où la libération d'acide nitrique polyphasique peut s'avérer bénéfique.

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