Polydisperse native pseudomonas flagellar (h) antigens and a...

A - Human Necessities – 61 – K

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167/135, 530/15.

A61K 39/104 (2006.01) C07K 3/12 (1985.01) C07K 15/04 (1985.01)

Patent

CA 1263307

ABSTRACT OF THE DISCLOSURE: Polydisperse native Pseudomonas flagellar (H) antigens have monomeric components each comprising certain amino acids, having a certain N-terminal amino acid sequence and a certain molecular weight and being free from pryrogenic substances, the ratio of the individual amino acids in the flagellar antigen of the individual amino acids in the flagellar antigen of the individual H-serotypes being stated, and a method of recovering these antigens from Pseudomonas aeruginosa bacterial cultures by treating the cultures with a detergent and separating the polydisperse native flagellar antigens from these cultures.

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