Polyene oxazoles and processes for their preparation

Details Polyene oxazoles and processes for their preparation Polyene oxazoles and processes for their preparation

C - Chemistry, Metallurgy

12

N

C12N 1/20 (2006.01) A61K 31/421 (2006.01) A61K 31/422 (2006.01) A61P 35/00 (2006.01) C07D 263/30 (2006.01) C07D 263/32 (2006.01) C07D 413/12 (2006.01) C12P 17/14 (2006.01) C12P 17/16 (2006.01)

Patent

CA 2470935

Novel polyene oxazole compounds of Formula I: (See formula I) are useful as cytotoxic agents. The polyene oxazoles may be made by fermentation of Streptomyces sparsogenes and optional post-biosynthesis chemical modification thereof.

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