Polyepitopic proteinic fragments of the hiv nef protein,...

Details Polyepitopic proteinic fragments of the hiv nef protein,... Polyepitopic proteinic fragments of the hiv nef protein,...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 39/21 (2006.01) A61K 39/395 (2006.01) C07K 14/025 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) C12N 15/31 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2375602

The invention relates to the use of polyepitopic fragments of a determined protein for the production of medicaments designed to prevent or treat pathologies in which said protein is recognized by the cellular immune system and said polyepitopic fragments are chosen from the HIV Nef protein. The invention also relates to polyepitopic proteinic fragments of the HIV Nef protein, a method for the production and use thereof, especially in the field of vaccination.

La présente invention a pour objet l'utilisation de fragments polyépitopiques d'une protéine déterminée pour la préparation de médicaments destinés à la prévention ou au traitement de pathologies dans lesquelles ladite protéine est reconnue par le système immunitaire cellulaire, lesdits fragments polyépitopiques étant choisis parmi ceux de la protéine Nef d'HIV. L'invention a également pour objet des fragments protéiques polyépitopiques de la protéine Nef d'HIV, leur procédé d'obtention, et leurs utilisations, notamment dans le domaine de la vaccination.

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