Polyethylene glycol erythropoietin conjugates

Details Polyethylene glycol erythropoietin conjugates Polyethylene glycol erythropoietin conjugates

C - Chemistry, Metallurgy

07

K

C07K 17/08 (2006.01) A61K 38/00 (2006.01) A61K 38/22 (2006.01) A61K 47/48 (2006.01) C07K 14/505 (2006.01)

Patent

CA 2659990

This invention relates to novel protein conjugates, in particular, to novel pegylated proteins, and their methods of making and use. One aspect of the present invention relates to pegylated-erythropoietin having greater clinical efficacy and stability during shipment and storage than current erythropoietin formulations.

Cette invention concerne de nouveaux conjugués de protéine, en particulier de nouvelles protéines pegylées, ainsi que leurs procédés de fabrication et leur utilisation. Sous l'un de ses aspects, la présente invention concerne de l'érythropoïétine pegylée dotée d'une efficacité clinique et d'une stabilité pendant l'acheminement et le stockage supérieures aux formulations courantes d'érythropoïétine.

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