Polyfunctional disulfide compound

Details Polyfunctional disulfide compound Polyfunctional disulfide compound

C - Chemistry, Metallurgy

07

D

260/277.8

C07D 213/71 (2006.01) C07D 213/89 (2006.01) C07D 277/78 (2006.01) C07D 401/12 (2006.01) G01N 33/535 (2006.01)

Patent

CA 1134830

ABSTRACT OF THE DISCLOSURE A novel polyfunctional disulfide compound of the formula Image where R is 2-benzothiazolyl or 2-pyridyl-N-oxide, and X is a spacer group having an alkylene group directly bound to the S-S group, is disclosed. It is useful as a cross- linking reagent having S-S exchange reactivity and which exhibits two different stepwise reactivities for compounds having a thiol group, and therefore is useful as a cross- linking agent for bound complexes of an enzyme and hapten, antigen or antibody, and as an immobilizing agent for an enzyme or hapten and a carrier.

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