Polyfunctional support material for complex nucleic acid...

Details Polyfunctional support material for complex nucleic acid... Polyfunctional support material for complex nucleic acid...

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) B01J 19/00 (2006.01) B01J 20/32 (2006.01) B01J 43/00 (2006.01)

Patent

CA 2403523

The invention relates to a material for the complex manipulation of nucleic acids as a platform technology for developing integrative, fully automatic systems for nucleic acid analysis. The inventive support material for complex nucleic acid analysis is characterised in that at least one covalently bonded layer is located on the surface, said layer bearing at least two different functional groups which are statistically distributed on the surface. At least one of the functional groups is negatively charged and at least one other functional group is positively charged or chemically reactive or has both of these properties.

Matière pour la manipulation complexe d'acides nucléiques en tant que plate-forme technologique en vue de la mise au point de systèmes intégrés pouvant être totalement automatisés pour l'analyse d'acides nucléiques. La matière selon la présente invention est caractérisée en ce qu'elle porte sur sa surface au moins une couche liée de manière covalente comportant au moins deux groupes fonctionnels différents qui se trouvent statistiquement répartis sur la surface. Au moins un des groupes fonctionnels présente une charge négative et au moins un autre groupe fonctionnel présente une charge positive ou une réactivité chimique, ou encore possède ces deux propriétés.

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