Polyhydronorharman synthase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/675 (2006.01) C07D 471/14 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2140953

Selected acid functional polyhydronorharman type derivatives effective as thromboxane synthase inhibitors having the formula: Image (II) where R1 and R2 are monovalent radicals, -(La)- is a linking group of 4 to 8 chain atoms, and A is an acidic group.

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