Polyhydroxyalkylpyrazine derivatives, preparation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 241/12 (2006.01) A61K 31/495 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2296739

The invention concerns medicines containing as active principle at least a compound of general formula (I) in which R1 represents the steroisomer forms of the chain (II): -(CHOH)3-CH2OH and either R2 represents a hydrogen atom and R3 represents the stereoisomer forms of the chain (III): -CH2-(CHOH)2-CH2OH or R2 represents the stereoisomer forms of chains (II): -(CHOH)3-CH2OH (II) or (III): -CH2-(CHOH)2-CH2OH and R3 represents a hydrogen atom or one of its salts, the novel stereoisomers of compounds of general formula (I), their salts and their preparation.

Médicaments contenant en tant que principe actif au moins un composé de formule générale (I) dans laquelle: R1 représente les formes stéréoisomères de la chaîne (II): -(CHOH)3-CH2OH et soit R2 représente un atome d'hydrogène et R3 représente les formes stéréoisomères de la chaîne (III): -CH2-(CHOH)2-CH2OH soit R2 représente les formes stéréoisomères des chaînes (II): -(CHOH)3-CH2OH ou (III): -CH2-(CHOH)2-CH2OH et R3 représente un atome d'hydrogène, ou un de ses sels, les nouveaux stéréoisomères des composés de formule générale (I), leurs sels et leur préparation.

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