Polyhydroxystilbenes as antipsoriatic agents and protein...

A - Human Necessities – 61 – K

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A61K 31/05 (2006.01) A61P 17/06 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2393297

Disclosed herein are compositions containing hydroxylstilbenes or their derivatives or analogues. The compositions are useful to inhibit protein kinease, and for the treatment of inflammatory diseases, including psoriasis , multiple sclerosis, rhumatoid arthritis, restinosis, inflammatory bowel disease, and inflammatory lung disease. They are also useful to treat surgical adhesions and graft rejection. Novel derivatives and analogues are also disclosed.

L'invention concerne des compositions contenant des hydroxylstilbènes ou leurs dérivés ou analogues. Ces compositions sont utiles pour inhiber la protéine kinase et traiter des maladies inflammatoires, notamment le psoriasis, la sclérose en plaques, l'arthrite rhumatoïde, la resténose, la maladie intestinale inflammatoire et la pneumopathie inflammatoire. Elles sont également utiles pour traiter les adhésions chirurgicales et le rejet de greffe. L'invention concerne en outre de nouveaux dérivés et analogues.

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