Polyketides and their synthesis

Details Polyketides and their synthesis Polyketides and their synthesis

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07D 498/18 (2006.01) C07H 17/08 (2006.01) C12N 1/21 (2006.01) C12N 9/00 (2006.01) C12N 9/88 (2006.01) C12N 9/96 (2006.01) C12N 15/52 (2006.01) C12N 15/76 (2006.01) C12P 1/00 (2006.01) C12P 19/26 (2006.01) C12P 19/62 (2006.01)

Patent

CA 2259463

A hybrid type I polyketide synthase gene typically containing a starter module and a plurality of heterologous extender modules is used to synthesise novel polyketides. It is preferably under the control of a type II polypolyketide synthase promoter e.g. <u>act</u> I of S. coelicolor.

Un gène de polykétide synthase hybride du type I contenant généralement un module de démarrage et plusieurs modules d'extension hétérologue est utilisé pour synthétiser de nouveaux polykétides, de préférence sous le contrôle d'un promoteur de polykétide synthase du type II, par exemple <u>act</u> I de S. coelicolor.

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