Polymer

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 73/02 (2006.01)

Patent

CA 2664462

The invention provides compositions comprising a polyamidoamine (PAA) polymer comprising a pendant disulphide, sulphydryl, or activated sulphydryl moiety, and methods for their manufacture. The invention extends to the use of such polyamidoamine polymers to form cross-linked compositions, and hydrogels comprising the same, and the use of such compositions in various biological and non-biological applications, such as the delivery of biomolecules to target sites, and for tracking fluid flows. The invention also provides carrier particles, which may be used to deliver biomolecules, and to methods of treatment. The invention also provides a fluid tracking system for monitoring fluid flow.

L'invention porte sur des compositions comprenant un polymère de polyamidoamine (PAA) composé d'une fraction de disulfure pendant, de mercapto ou de mercapto activé, ainsi que sur leurs procédés de fabrication. L'invention peut aussi s'étendre à l'utilisation de ces polymères de polyamidoamine de façon à obtenir des compositions réticulées, et des hydrogels les comprenant, et à l'utilisation de ces compositions dans diverses applications biologiques et non biologiques, telles que l'administration de biomolécules sur des sites cibles, et dans le suivi d'écoulement de fluide. L'invention porte également sur des particules porteuses qui peuvent être utilisées pour administrer des biomolécules et sur des méthodes de traitement, et également sur un système de suivi de fluide permettant de surveiller l'écoulement d'un fluide.

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