Polymer-based anti-cancer agents

Details Polymer-based anti-cancer agents Polymer-based anti-cancer agents

A - Human Necessities

61

K

A61K 31/765 (2006.01) A61K 31/785 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2648007

The present invention relates to the use of amphiphilic block copolymers for treating and preventing cancer, and in particular by reducing the proliferation rate of cancer cells. Preferred block copolymers comprises a central hydrophobic chain, preferably a polypropylene oxide chain, two which at least two hydrophilic side chains, preferably polyethylene oxide chains, are connected.

L'invention concerne l'utilisation de copolymères séquencés amphiphiles destinés au traitement et à la prévention du cancer qui permettent, en particulier, de réduire la vitesse de prolifération du cancer. Des copolymères séquencés préférés comprennent une chaîne hydrophobe centrale, de préférence une chaîne d'oxyde de polypropylène, à laquelle sont reliées au moins deux chaînes latérales hydrophiles, de préférence des chaînes d'oxyde de polyéthylène.

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