A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 31/10 (2006.01) A61L 31/16 (2006.01) B05D 1/02 (2006.01) B05D 3/00 (2006.01)
Patent
CA 2615452
A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.
L'invention concerne un procédé permettant de déposer un enrobage comprenant un polymère et un agent pharmaceutique sur un substrat et comprenant les étapes suivantes consistant: à décharger au moins un agent pharmaceutique selon une morphologie recherchée sur le plan thérapeutique sous la forme d'une poudre sèche à travers un premier orifice; à décharger au moins un polymère sous la forme d'une poudre sèche à travers un second orifice; à déposer le polymère et/ou les particules pharmaceutiques sur le substrat, un potentiel électrique étant maintenu entre le substrat et les particules pharmaceutiques et/ou polymères, formant ainsi l'enrobage; et à fritter l'enrobage dans des conditions ne modifiant sensiblement pas la morphologie de l'agent pharmaceutique.
Cole Mike
Deyoung James
Mcclain James B.
Smoke Clint
Taylor Doug
Mbm Intellectual Property Law Llp
Micell Technologies Inc.
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