Polymer coatings on medical devices

Details Polymer coatings on medical devices Polymer coatings on medical devices

A - Human Necessities

61

L

A61L 27/10 (2006.01)

Patent

CA 2687031

A medical device, for example a stent, has a surface which in use contacts body tissue, wherein said surface has on it a biocompatible coating layer comprising a polymer having covalently bound allyl-terminated pendent groups, said pendent groups comprising a moiety selected from -0-CH2-CH=CH2 -S-CH2-CH=CH2 -S (=0) -CH2-CH=CH2 -Se-CH2-CH=CH2 and -Se (=0 J-CH2-CH=CH2. This surface has good biocompatibility and can bind strongly to a metallic surface. The polymer may be made from an electropolymerisable monomer, e.g. a pyrrole.

Un dispositif médical, par exemple un stent, présente une surface qui, en utilisation, entre en contact avec un tissu corporel. Ladite surface est munie de groupes pendants terminés par un allyle et liés de façon covalente. Les groupes pendants comprennent une fraction choisie parmi -O-CH2-CH=CH2, -S-CH2-CH=CH2, -S(=O), -CH2-CH=CH2, -Se-CH2-CH=CH2 et -Se(=O) -CH2-CH=CH2. Cette surface présente une bonne biocompatibilité et peut se lier fortement à une surface métallique. Le polymère peut être fait d'un monomère électropolymérisable, par exemple un pyrrole.

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