Polymer compositions for polynucleotide delivery

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01) A61P 29/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2364006

The present invention provides a composition comprising: (a) a nucleic acid or an oligonucleotide; and (b) a block copolymer containing a hydrophilic block that carries functional groups that provide the block with a positive charge. These compositions may be used to deliver a nucleic acid or an oligonucleotide to a cell.

L'invention concerne un composition comprenant: (a) un acide nucléique ou un oligonucléotide; et (b) un copolymère séquencé contenant un bloc hydrophile qui comporte des groupes fonctionnels fournissant une charge positive au bloc. On peut utiliser ces compositions pour administrer un acide nucléique ou un oligonucléotide à une cellule.

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