Polymer conjugates of interferon beta-1a and their uses

Details Polymer conjugates of interferon beta-1a and their uses Polymer conjugates of interferon beta-1a and their uses

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 38/19 (2006.01)

Patent

CA 2345138

An interferon beta polypeptide comprising interferon-beta 1a coupled to a polymer containing a polyalkylene glycol moiety wherein the interferon-beta-1a and the polyalkylene glycol moiety are arranged such that the interferon-beta-1a has an enhanced activity relative to another therapeutic form of interferon beta (interferon-beta-1b) and exhibits no decrease in activity as compared to non-conjugated interferon-beta-1a. The conjugates of the invention are usefully employed in therapeutic as well as non-therapeutic, e.g., diagnostic, applications.

L'invention concerne un polypeptide à interféron bêta comprenant un interféron bêta 1a couplé à un polymère qui renferme une fraction polyalkylène glycol. L'interféron et la fraction sont disposés de sorte que l'interféron bêta-1a ait une activité améliorée par rapport à une autre forme thérapeutique d'interféron bêta (interféron bêta 1b) et ne présente aucune baisse d'activité par rapport à l'interféron bêta 1a non conjugué. Les conjugués considérés sont utiles dans le domaine thérapeutique et non thérapeutique (par exemple, applications de diagnostic).

Affiliated with

Also associated with

Rating

Polymer conjugates of interferon beta-1a and their uses does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymer conjugates of interferon beta-1a and their uses, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymer conjugates of interferon beta-1a and their uses will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2046195