Polymer conjugates of therapeutic peptides

A - Human Necessities – 61 – K

Patent

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A61K 47/48 (2006.01)

Patent

CA 2737040

The invention provides peptides that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water- soluble oligomer.

L'invention concerne des peptides qui sont chimiquement modifiés par attachement covalent d'un oligomère hydrosoluble. Lorsqu'on administre un conjugué de l'invention par l'une quelconque parmi plusieurs voies d'administration, il présente des caractéristiques qui sont différentes des caractéristiques du peptide qui n'est pas attaché à l'oligomère hydrosoluble.

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