Polymer-coupled peptidases

Details Polymer-coupled peptidases Polymer-coupled peptidases

C - Chemistry, Metallurgy

12

Q

C12Q 1/56 (2006.01) A61K 35/14 (2006.01) C12N 9/64 (2006.01) C12N 9/74 (2006.01) C12Q 1/37 (2006.01)

Patent

CA 2731664

The present invention is directed to a simple process for the modification of the specificity of a peptidase of the hemostatic system by coupling polymers to the peptidase causing it to lose its reactivity in the hemostatic system, but enabling it to continue to react with certain inhibitors, effectors and substrates. The invention is furthermore directed to processes for the detection or quantitative determination of inhibitors of the peptidase in bodily fluids or other samples as well as to processes for their neutralization and/or removal from liquids. Finally, the invention allows the use of a polymer-coupled peptidase as drug and furthermore provides a device which makes use of such a peptidase in the removal of peptidase inhibitors from samples or from the bloodstream of a patient.

Affiliated with

Also associated with

Rating

Polymer-coupled peptidases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymer-coupled peptidases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymer-coupled peptidases will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2023455