Polymer-factor ix moiety conjugates

Details Polymer-factor ix moiety conjugates Polymer-factor ix moiety conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61P 7/04 (2006.01)

Patent

CA 2571292

Conjugates of a Factor IX moiety and one or more water-solute e polymers are provided. Typically, the water-soluble polymer is polyethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.

Cette invention concerne des conjugués d'une fraction Facteur IX et d'un ou plusieurs polymères hydrosolubles. D'ordinaire, le polymère hydrosoluble est un poly(éthylène glycol) ou un dérivé de celui-ci. Cette invention concerne également, (entre autres choses) des compositions renfermant les conjugués de cette invention, des procédés de production de ces conjugués et des méthodes permettant d'administrer à un patient les compositions renfermant les conjugués.

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